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This medication has been approved for use in treatments for insomnia. Eszopiclone has been used since 1992 when it was first prescribed in Europe. Following this, it has been approved for use in the USA since 2005, under the brand name Lunesta. Clinical trials show it is just as effective as other Z drugs which are prescribed for insomnia.



Insomnia is a condition that continues to become more prominent, year after year. Being the most common sleep disorder in the world, it is thought to affect at least 30% of the global population at least once in a lifetime.

How Does Eszopiclone Work?

This medication decreases sleep latency and helps to initiate sleep quickly. The precise mechanism of action of Eszopiclone is currently unknown, however, it is thought to work in similar ways to other non-benzodiazepines. Similar medications work by binding to the GABA receptors which are found in the central nervous system (CNS).

GABA is a neurochemical which is responsible for calming the mind and body. When these types of medications bind to the GABA receptors, the effects of GABA become elevated, making the calming effects much stronger. These effects, slow down thought patterns and internal messages in the body.



Is Eszopiclone Safe for Everyone?

This medication has been trialled and tested before approval by the FDA and original manufacturers. FDA approval is only given to medications that show more positive characteristics than negative ones. Despite this, there are some people who should be careful when taking Eszopiclone. Those with breathing problems, including sleep apnoea, should be vigilant and seek advice first.

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The same precautions should also be extended to patients over the age of 65. Common side effects include; drowsiness, unsteadiness, and dry mouth. For a full list of side effects, be sure to read the patient information leaflet.

Think Before You Buy Eszopiclone

When taking any medication safety is the number one concern. People take medicines to help themselves get better, not worse. For this reason, it is very important that proper usage is followed and the duration of use, which is 1-2 weeks, is never exceeded. By taking more than advised and prolonging the use of this medication, people are more at risk of adverse effects.

If this medication is used as part of a treatment plan, which includes diet changes and some healthy wellness activities, people have a higher chance of beating their insomnia. Such changes may include making efforts to avoid blue light in the evening, exercising, and meditating.


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